ES405553A1 - Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos. - Google Patents
Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos.Info
- Publication number
- ES405553A1 ES405553A1 ES405553A ES405553A ES405553A1 ES 405553 A1 ES405553 A1 ES 405553A1 ES 405553 A ES405553 A ES 405553A ES 405553 A ES405553 A ES 405553A ES 405553 A1 ES405553 A1 ES 405553A1
- Authority
- ES
- Spain
- Prior art keywords
- esters
- carboxylic acids
- amino derivatives
- pyrazolopyridine
- pyrazolopyridine carboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 abstract 1
- IVOMOUWHDPKRLL-UHFFFAOYSA-N UNPD107823 Natural products O1C2COP(O)(=O)OC2C(O)C1N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000002716 ataractic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16953671A | 1971-08-05 | 1971-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES405553A1 true ES405553A1 (es) | 1975-07-01 |
Family
ID=22616112
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405553A Expired ES405553A1 (es) | 1971-08-05 | 1972-08-04 | Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos. |
| ES413941A Expired ES413941A1 (es) | 1971-08-05 | 1973-04-19 | Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin - 5 - carboxilicos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES413941A Expired ES413941A1 (es) | 1971-08-05 | 1973-04-19 | Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin - 5 - carboxilicos. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3755340A (en]) |
| JP (3) | JPS5637237B2 (en]) |
| AR (2) | AR199280A1 (en]) |
| AU (1) | AU462839B2 (en]) |
| BE (1) | BE787249A (en]) |
| CA (1) | CA997350A (en]) |
| CH (3) | CH553798A (en]) |
| DE (1) | DE2237765A1 (en]) |
| ES (2) | ES405553A1 (en]) |
| FR (1) | FR2150737B1 (en]) |
| GB (1) | GB1402172A (en]) |
| HU (1) | HU164519B (en]) |
| IE (1) | IE36600B1 (en]) |
| NL (1) | NL176365C (en]) |
| PH (2) | PH10047A (en]) |
| YU (1) | YU35138B (en]) |
| ZA (1) | ZA724745B (en]) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984422A (en) * | 1972-06-16 | 1976-10-05 | E. R. Squibb & Sons, Inc. | Amino derivatives of [4,3-c]pyrazolopyridine carboxylic acids and esters |
| US3835144A (en) * | 1972-06-16 | 1974-09-10 | Squibb & Sons Inc | Amino derivatives of (4,3-c pyrazolopyridine cabroxylic acids and esters |
| US3957782A (en) * | 1974-12-16 | 1976-05-18 | E. R. Squibb & Sons, Inc. | Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides |
| US3996233A (en) * | 1975-02-10 | 1976-12-07 | E. R. Squibb & Sons, Inc. | Amino derivatives of imidazo[4,5-b]pyridines |
| US4038283A (en) * | 1975-04-30 | 1977-07-26 | E. R. Squibb & Sons, Inc. | 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters |
| CA1071207A (en) * | 1975-04-30 | 1980-02-05 | Theodor Denzel | 4-amino derivatives of 2h-pyrazolo (3,4-b) pyridine-5-carboxylic acids and esters |
| US3985760A (en) * | 1975-09-11 | 1976-10-12 | E. R. Squibb & Sons, Inc. | Amino derivatives of 6-phenylisoxazolo[5,4-b]pyridines |
| JPS531041U (en]) * | 1976-06-22 | 1978-01-07 | ||
| US4364948A (en) * | 1981-09-28 | 1982-12-21 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine compounds |
| GB8310266D0 (en) * | 1982-05-12 | 1983-05-18 | Ici America Inc | Pyrazolopyridine compounds |
| US4552883A (en) * | 1982-06-15 | 1985-11-12 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use |
| IT1154024B (it) * | 1982-09-22 | 1987-01-21 | Lepetit Spa | Derivati pridinici e procedimento per la loro produzione |
| GB8425104D0 (en) * | 1984-10-04 | 1984-11-07 | Ici America Inc | Amide derivatives |
| JPH0522500Y2 (en]) * | 1984-12-27 | 1993-06-10 | ||
| JPS61113659U (en]) * | 1984-12-28 | 1986-07-18 | ||
| ATE71934T1 (de) | 1985-06-07 | 1992-02-15 | Ici America Inc | Selektionierte difluorverbindungen. |
| JPS62103137U (en]) * | 1985-12-20 | 1987-07-01 | ||
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| JPS63188572U (en]) * | 1987-05-28 | 1988-12-02 | ||
| GB9716161D0 (en) | 1997-08-01 | 1997-10-08 | Zeneca Ltd | Process |
| JP2002508324A (ja) * | 1997-12-13 | 2002-03-19 | ブリストル−マイヤーズ スクイブ カンパニー | サイクリン依存性キナーゼ阻害剤としてのピラゾロ［３，４−ｂ］ピリジンの使用 |
| US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
| GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| JP2006503108A (ja) * | 2002-09-16 | 2006-01-26 | グラクソ グループ リミテッド | ピラゾロ［３，４−ｂ］ピリジン化合物およびそれのホスホジエステラーゼ阻害薬としての使用 |
| WO2005058892A1 (en) * | 2003-12-19 | 2005-06-30 | Glaxo Group Limited | Pyrazolo [3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors |
| GB0405937D0 (en) * | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
| US7709497B2 (en) * | 2004-03-16 | 2010-05-04 | Glaxo Group Limited | Pyrazolo[3,4-b]pyridine compound, and its use as a PDE4 inhibitor |
| US8389510B2 (en) * | 2005-11-18 | 2013-03-05 | Astrazeneca Ab | Crystalline forms |
| JP2010531292A (ja) * | 2006-12-20 | 2010-09-24 | アストラゼネカ・アクチエボラーグ | 化合物及びその使用 |
| TW200908968A (en) | 2007-05-29 | 2009-03-01 | Sgx Pharmaceuticals Inc | Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators |
| TW200946526A (en) * | 2008-02-06 | 2009-11-16 | Glaxo Group Ltd | Dual pharmacophores-PDE4-muscarinic antagonistics |
| TW201000476A (en) * | 2008-02-06 | 2010-01-01 | Glaxo Group Ltd | Dual pharmacophores-PDE4-muscarinic antagonistics |
| CL2009000249A1 (es) * | 2008-02-06 | 2009-09-11 | Glaxo Group Ltd | Compuestos derivados de pirazolo[3,4-b] piridin-butanodiamida; composicion farmaceutica; y su uso en el tratamiento del asma, enfermedad pulmonar obstructiva cronica, rinitis, dermatitis atopica, psoriasis. |
-
0
- BE BE787249D patent/BE787249A/xx not_active IP Right Cessation
-
1971
- 1971-08-05 US US00169536A patent/US3755340A/en not_active Expired - Lifetime
-
1972
- 1972-07-11 ZA ZA724745A patent/ZA724745B/xx unknown
- 1972-07-13 CA CA147,053A patent/CA997350A/en not_active Expired
- 1972-07-25 IE IE1049/72A patent/IE36600B1/xx unknown
- 1972-07-31 AU AU45146/72A patent/AU462839B2/en not_active Expired
- 1972-08-01 DE DE2237765A patent/DE2237765A1/de not_active Withdrawn
- 1972-08-02 GB GB3615572A patent/GB1402172A/en not_active Expired
- 1972-08-04 NL NLAANVRAGE7210701,A patent/NL176365C/xx not_active IP Right Cessation
- 1972-08-04 CH CH1161072A patent/CH553798A/fr not_active IP Right Cessation
- 1972-08-04 HU HUSU764A patent/HU164519B/hu unknown
- 1972-08-04 ES ES405553A patent/ES405553A1/es not_active Expired
- 1972-08-04 CH CH179674A patent/CH553800A/fr not_active IP Right Cessation
- 1972-08-04 FR FR7228285A patent/FR2150737B1/fr not_active Expired
- 1972-08-04 YU YU2020/72A patent/YU35138B/xx unknown
- 1972-08-04 CH CH179774A patent/CH549590A/fr not_active IP Right Cessation
- 1972-08-05 JP JP7872872A patent/JPS5637237B2/ja not_active Expired
- 1972-08-07 AR AR243467A patent/AR199280A1/es active
-
1973
- 1973-04-19 ES ES413941A patent/ES413941A1/es not_active Expired
- 1973-05-08 AR AR247901A patent/AR199294A1/es active
- 1973-08-22 PH PH14939A patent/PH10047A/en unknown
-
1975
- 1975-07-16 PH PH17388A patent/PH13781A/en unknown
-
1980
- 1980-06-19 JP JP8339780A patent/JPS5622784A/ja active Granted
- 1980-06-19 JP JP55083398A patent/JPS597703B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU4514672A (en) | 1974-02-07 |
| JPS5745440B2 (en]) | 1982-09-28 |
| CH553800A (fr) | 1974-09-13 |
| HU164519B (en]) | 1974-02-28 |
| JPS4826796A (en]) | 1973-04-09 |
| BE787249A (fr) | 1973-02-05 |
| FR2150737B1 (en]) | 1975-06-20 |
| CH553798A (fr) | 1974-09-13 |
| JPS5637237B2 (en]) | 1981-08-29 |
| ES413941A1 (es) | 1976-06-01 |
| IE36600L (en) | 1973-02-05 |
| GB1402172A (en) | 1975-08-06 |
| AU462839B2 (en) | 1975-07-10 |
| JPS597703B2 (ja) | 1984-02-20 |
| ZA724745B (en) | 1973-04-25 |
| JPS5622784A (en) | 1981-03-03 |
| NL176365C (nl) | 1985-04-01 |
| YU35138B (en) | 1980-09-25 |
| CA997350A (en) | 1976-09-21 |
| YU202072A (en) | 1980-03-15 |
| IE36600B1 (en) | 1976-12-08 |
| DE2237765A1 (de) | 1973-02-08 |
| PH10047A (en) | 1976-07-27 |
| US3755340A (en) | 1973-08-28 |
| CH549590A (fr) | 1974-05-31 |
| AR199294A1 (es) | 1974-08-23 |
| NL176365B (nl) | 1984-11-01 |
| FR2150737A1 (en]) | 1973-04-13 |
| PH13781A (en) | 1980-09-26 |
| NL7210701A (en]) | 1973-02-07 |
| JPS5622768A (en) | 1981-03-03 |
| AR199280A1 (es) | 1974-08-23 |
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